Plant-based alternative in estrogen therapy: Evamist spray



The plant-based alternative

Evamist contains what is called “17β-estradiol,” an estrogen made from plants, and similar to the kind your ovaries made before menopause. Some of the older prescription estrogen therapies are still made from animal products, such as conjugated equine estrogens, which are not the same as the estrogens your body naturally makes. However, there is no known evidence that plant-based estrogen is safer than conjugated equine estrogen (made from the urine of a pregnant mare).^1-3

The transdermal alternative

Because Evamist is transdermal (delivered through the skin), the estrogen does not first pass through the liver, but instead goes directly to the bloodstream and acts to reduce hot flashes in your system.^3,4 While there is no evidence proving estrogen delivered through the skin is safer than taking it orally, with transdermal therapy you may be able to use a lower dose of medication to provide relief. The Evamist applicator is designed to release the same low dose of estrogen with each spray, so you will always apply the right amount of medication.¹ Evamist is a plant-based alternative in estrogen therapy. Now, read how easy it is to use!

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Important Safety Information

Evamist™ is approved by the FDA for use after menopause to reduce moderate-to-severe hot flashes.

Estrogens increase the chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using Evamist. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia. Using estrogens, with or without progestins, may increase your chance of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogen, with or without progestins, may increase your risk of dementia, based on a study of women age 65 years or older. Evamist should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the past year; currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.

The most common side effects that may occur with Evamist are headache, breast tenderness, the common cold, nipple pain, back pain, nausea, and joint pain.

You and your healthcare provider should talk regularly about whether you still need treatment with Evamist.

Please see full prescribing information for Evamist.